Structure of PDB 4ra0 Chain B

Receptor sequence
>4ra0B (length=377) Species: 9606 (Homo sapiens) [Search protein sequence]
LPCVPFSVAKSVKSLYLGRMFSGTPVIRLRFKRLQPTRLVAEFDFRTFDP
EGILLFAGGHQDSTWIVLALRAGRLELQLRYNGVGRVTSSGPVINHGMWQ
TISVEELARNLVIKVNRDAVMKIAVAGDLFQPERGLYHLNLTVGGIPFHE
KDLVQPINPRLDGCMRSWNWLNGEDTTIQETVKVNTRMQCFSVTERGSFY
PGSGFAFYSLDYMTWEVEVVAHIRPAADTGVLFALWAPDLRAVPLSVALV
DKQLVVLAVEHTALALMEIKVCDGQEHVVTVSLRDGEATLEVDGTRGQSE
VSAAQLQERLAVLERHLRSPVLTFAGGLPDVPVTSAPVTAFYRGCMTLEV
NRRLLDLDEAAYKHSDITAHSCPPVEP
3D structure
PDB4ra0 An engineered Axl 'decoy receptor' effectively silences the Gas6-Axl signaling axis.
ChainB
Resolution3.07 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA B D329 E331 R440 D656 D49 E51 R160 D358
External links
PDB RCSB:4ra0, PDBe:4ra0, PDBj:4ra0
PDBsum4ra0
PubMed25242553
UniProtQ14393|GAS6_HUMAN Growth arrest-specific protein 6 (Gene Name=GAS6)

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