Structure of PDB 4r73 Chain B

Receptor sequence
>4r73B (length=319) Species: 715 (Actinobacillus pleuropneumoniae) [Search protein sequence]
SKGRLVIYCSATNVMCENAAKTFEQKYDVKTSFIRNGSGSTFAKIEAEKN
NPQADVWYGGTLDPQSQAGELGLLEAYRSPNIDQIMPKFQDPAKVKGNLS
SAVYIGILGFAVNTERLKKLGIEKIPQCWNDLTDPKLKGEIQIADPQSSG
TAYTAIATFAQLWGEDKAFDYFKHLHPNISQYTKSGITPARNAARGETTV
GIGFLHDYALEKEQGAPLEMVVPCEGTGYELGGVSILKGARNLDNAKLFV
DFALSKEGQETAWKKGQALQTLTNTTAEQSPLAFDLTKLKLIDYDFEKYG
ASDERKRLINKWVDEIKLA
3D structure
PDB4r73 Active Transport of Phosphorylated Carbohydrates Promotes Intestinal Colonization and Transmission of a Bacterial Pathogen.
ChainB
Resolution1.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 G6P B R34 S37 G59 Y103 S148 G149 T150 G185 I186 H205 D206 E229 Q269 R35 S38 G60 Y104 S149 G150 T151 G186 I187 H206 D207 E230 Q270 MOAD: Kd=23nM
BS02 M6P B R34 S37 G59 Y103 S148 G149 T150 G185 I186 H205 D206 E229 R35 S38 G60 Y104 S149 G150 T151 G186 I187 H206 D207 E230 MOAD: Kd=960nM
Gene Ontology
Molecular Function
GO:0030975 thiamine binding
GO:0030976 thiamine pyrophosphate binding
Biological Process
GO:0015888 thiamine transport
Cellular Component
GO:0030288 outer membrane-bounded periplasmic space

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4r73, PDBe:4r73, PDBj:4r73
PDBsum4r73
PubMed26295949
UniProtA3N294

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