Structure of PDB 4r5g Chain B

Receptor sequence
>4r5gB (length=209) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
MHHHHHHIEGRVLLLDVTPLSLGIETMGGVMTTLIAKNTTIPTKHSQVFS
TAEDNQSAVTIHVLQGERKRAADNKSLGQFNLDGINPAPRGMPQIEVTFD
IDADGILHVSAKDKNSGKEQKITIKASSGLNEDEIQKMVRDAEANAEADR
KFEELVQTRNQGDHLLHSTRKQVEEDDKTAIESALTALETALKGKAAIEA
KMQELAQVS
3D structure
PDB4r5g Structural Basis for the Inhibition of HSP70 and DnaK Chaperones by Small-Molecule Targeting of a C-Terminal Allosteric Pocket.
ChainB
Resolution3.4501 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 3JE B L392 T395 P396 L399 A503 S504 L15 T18 P19 L22 A126 S127 PDBbind-CN: -logKd/Ki=5.22,Kd=6.0uM
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0140662 ATP-dependent protein folding chaperone

View graph for
Molecular Function
External links
PDB RCSB:4r5g, PDBe:4r5g, PDBj:4r5g
PDBsum4r5g
PubMed25148104
UniProtP0A6Y8|DNAK_ECOLI Chaperone protein DnaK (Gene Name=dnaK)

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