Structure of PDB 4qo1 Chain B

Receptor sequence
>4qo1B (length=199) Species: 9606 (Homo sapiens) [Search protein sequence]
PLSSSVPSQKTYQGSYGFRLGFLHSGTAKSVTCTYSPALNKMFCQLAKTC
PVQLWVDSTPPPGTRVRAMAIYKQSQHMTEVVRRCPHHERCSDSDGLAPP
QHLIRVEGNLRVEYLDDRNTFRHSVVVPYEPPEVGSDCTTIHYNYMCNSS
CMGGMNRRPILTIITLEDSSGNLLGRNSFEVRVCACPGRDRRTEEENLR
3D structure
PDB4qo1 A nanobody modulates the p53 transcriptional program without perturbing its functional architecture.
ChainB
Resolution1.924 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN B C176 H179 C238 C242 C85 H88 C147 C151
Gene Ontology
Molecular Function
GO:0000976 transcription cis-regulatory region binding
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006915 apoptotic process
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4qo1, PDBe:4qo1, PDBj:4qo1
PDBsum4qo1
PubMed25324313
UniProtP04637|P53_HUMAN Cellular tumor antigen p53 (Gene Name=TP53)

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