Structure of PDB 4qmg Chain B

Receptor sequence
>4qmgB (length=309) Species: 9606 (Homo sapiens) [Search protein sequence]
PTVQRGIIKMVLSGCAIIVRGQPRGGPPPERQINLSNIRAGNLARRAAAT
QPDAKDTPDEPWAFPAREFLRKKLIGKEVCFTIENKTPQGREYGMIYLGK
DTNGENIAESLVAEGLATRRNNPEQNRLSECEEQAKAAKKGMWSEGNGSH
TIRDLKYTIENPRHFVDSHHQKPVNAIIEHVRDGSVVRALLLPDYYLVTV
MLSGIKCPTFRDGSETPEPFAAEAKFFTESRLLQRDVQIILESCHNQNIL
GTILHPNGNITELLLKEGFARCVDWSIAVYTRGAEKLRAAERFAKERRLR
IWRDYVAPT
3D structure
PDB4qmg Structural Insights into the Tumor-Promoting Function of the MTDH-SND1 Complex.
ChainB
Resolution2.701 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.31.1: micrococcal nuclease.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide B H269 W299 H245 W275
BS02 peptide B G42 P43 R87 K88 G92 F244 E247 F250 S254 R255 L256 R259 D260 H279 N281 F293 R324 R327 G26 P27 R71 K72 G76 F220 E223 F226 S230 R231 L232 R235 D236 H255 N257 F269 R300 R303
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0004518 nuclease activity

View graph for
Molecular Function
External links
PDB RCSB:4qmg, PDBe:4qmg, PDBj:4qmg
PDBsum4qmg
PubMed25242325
UniProtQ7KZF4|SND1_HUMAN Staphylococcal nuclease domain-containing protein 1 (Gene Name=SND1)

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