Structure of PDB 4qgu Chain B

Receptor sequence
>4qguB (length=191) Species: 9606 (Homo sapiens) [Search protein sequence]
NVLQKRPVIVKVLSTTKPFEYETPEMEKKIMFHATVATQTQFFHVKVLNT
SLKEKFNGKKIIIISDYLEYDSLLEVNEESTVSEAGPQTFEVPNKIINRA
KETLKIDILHKQASGNIVYGVFMLHKKTVNQKTTIYEIQDDRGKMDVVGT
GQCHNIPCEEGDKLQLFCFRLRKKNQMSKLISEMHSFIQIK
3D structure
PDB4qgu New insights into the structural basis of DNA recognition by HINa and HINb domains of IFI16.
ChainB
Resolution2.545 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B S312 R370 K371 N373 Q374 S114 R172 K173 N175 Q176
Gene Ontology
Biological Process
GO:0002218 activation of innate immune response
GO:0035458 cellular response to interferon-beta

View graph for
Biological Process
External links
PDB RCSB:4qgu, PDBe:4qgu, PDBj:4qgu
PDBsum4qgu
PubMed26246511
UniProtQ16666|IF16_HUMAN Gamma-interferon-inducible protein 16 (Gene Name=IFI16)

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