Structure of PDB 4qfs Chain B

Receptor sequence
>4qfsB (length=158) Species: 10116 (Rattus norvegicus) [Search protein sequence]
PTVFRWTGGGKEVYLSGSFNNWSKLPLTRDQNNFVAILDLPEGEHQYKFF
VDGQWTHDPSEPIVTSQLGTVNNIIQVKKTDFEVFDALMVDSQKAPPILP
PHLLQVILNKCDPALLPEPNHVMLNHLYALSIKDGVMVLSATHRYKKKYV
TTLLYKPI
3D structure
PDB4qfs Structural Basis for AMPK Activation: Natural and Synthetic Ligands Regulate Kinase Activity from Opposite Poles by Different Molecular Mechanisms.
ChainB
Resolution3.55 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 32H B R83 D108 V113 R5 D30 V35 PDBbind-CN: -logKd/Ki=6.05,Kd=0.9uM
External links
PDB RCSB:4qfs, PDBe:4qfs, PDBj:4qfs
PDBsum4qfs
PubMed25066137
UniProtP80386|AAKB1_RAT 5'-AMP-activated protein kinase subunit beta-1 (Gene Name=Prkab1)

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