Structure of PDB 4pza Chain B

Receptor sequence
>4pzaB (length=217) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence]
RARRLVMLRHGQTDYNVGSRMQGQLDTELSELGRTQAVAAAEVLGKRQPL
LIVSSDLRRAYDTAVKLGERTGLVVRVDTRLRETHLGDWQGLTHAQIDAD
APGARLAWREDATWAPHGGESRVDVAARSRPLVAELVASEPEWGGADEPD
RPVVLVAHGGLIAALSAALLKLPVANWPALGGMGNASWTQLSGHWAPGSD
FESIRWRLDVWNASAQV
3D structure
PDB4pza Mechanism of dephosphorylation of glucosyl-3-phosphoglycerate by a histidine phosphatase
ChainB
Resolution1.776 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H11 R60 E84
Catalytic site (residue number reindexed from 1) H10 R59 E83
Enzyme Commision number 3.1.3.70: mannosyl-3-phosphoglycerate phosphatase.
3.1.3.85: glucosyl-3-phosphoglycerate phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PO4 B R10 H11 R60 E84 H159 G160 R9 H10 R59 E83 H158 G159
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0016787 hydrolase activity
GO:0016791 phosphatase activity
GO:0050531 mannosyl-3-phosphoglycerate phosphatase activity
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Cellular Component
External links
PDB RCSB:4pza, PDBe:4pza, PDBj:4pza
PDBsum4pza
PubMed24914210
UniProtP9WIC6|GPGP_MYCTO Glucosyl-3-phosphoglycerate phosphatase (Gene Name=gpgP)

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