Structure of PDB 4pwi Chain B

Receptor sequence
>4pwiB (length=111) Species: 9606 (Homo sapiens) [Search protein sequence]
CPLMVKVLDAVRGSPAINVAMHVFRKAADDTWEPFASGKTSESGELHGLT
TEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDRYTIAALLSP
YSYSTTAVVTN
3D structure
PDB4pwi Inhibitory Activities of Propolis and Its Promising Component, Caffeic Acid Phenethyl Ester, against Amyloidogenesis of Human Transthyretin
ChainB
Resolution1.494 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ROA B M13 K15 T106 L110 S117 M4 K6 T93 L97 S104 BindingDB: EC50=8600nM
External links
PDB RCSB:4pwi, PDBe:4pwi, PDBj:4pwi
PDBsum4pwi
PubMed25314129
UniProtP02766|TTHY_HUMAN Transthyretin (Gene Name=TTR)

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