Structure of PDB 4pwf Chain B

Receptor sequence
>4pwfB (length=114) Species: 9606 (Homo sapiens) [Search protein sequence]
CPLMVKVLDAVRGSPAINVAMHVFRKAADDTWEPFASGKTSESGELHGLT
TEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAA
LLSPYSYSTTAVVT
3D structure
PDB4pwf Inhibitory Activities of Propolis and Its Promising Component, Caffeic Acid Phenethyl Ester, against Amyloidogenesis of Human Transthyretin
ChainB
Resolution1.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PWF B T106 A108 L110 S117 T118 T119 V121 T97 A99 L101 S108 T109 T110 V112 BindingDB: EC50=7900nM
External links
PDB RCSB:4pwf, PDBe:4pwf, PDBj:4pwf
PDBsum4pwf
PubMed25314129
UniProtP02766|TTHY_HUMAN Transthyretin (Gene Name=TTR)

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