Structure of PDB 4pr3 Chain B

Receptor sequence
>4pr3B (length=199) Species: 224914 (Brucella melitensis bv. 1 str. 16M) [Search protein sequence]
NAMKTVAGKRLLYVMAADAEYGRHLAKLFTPLMIGVGPVEAAVNLASALA
HLKLAGDMPDLVISLGSAGSAKLPQAEVYQVSSVSYRDMDASPIGFEKGV
TPFLDLPETVELPFRVAGIDTASLSTGGNIVSGKAYERIEADMVDMETYA
CLRACQAVGVPLLGLRGISDGASELHVIDEKLAGAVARVERAVADGLLS
3D structure
PDB4pr3 Crystal structure and biochemical studies of Brucella melitensis 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase
ChainB
Resolution2.606 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.2.16: methylthioadenosine nucleosidase.
3.2.2.9: adenosylhomocysteine nucleosidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADE B S65 A66 G67 I128 V129 V142 S167 D168 S67 A68 G69 I130 V131 V144 S169 D170
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0008782 adenosylhomocysteine nucleosidase activity
GO:0008930 methylthioadenosine nucleosidase activity
GO:0016798 hydrolase activity, acting on glycosyl bonds
Biological Process
GO:0009116 nucleoside metabolic process

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Molecular Function
View graph for
Biological Process
External links
PDB RCSB:4pr3, PDBe:4pr3, PDBj:4pr3
PDBsum4pr3
PubMed24657441
UniProtQ8YBL1

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