Structure of PDB 4ppe Chain B

Receptor sequence
>4ppeB (length=67) Species: 9606 (Homo sapiens) [Search protein sequence]
LRPSGTVSCPICMDGYSEIVQNGRLIVSTECGHVFCSQCLRDSLKNANTC
PTCRKKINHKRYHPIYI
3D structure
PDB4ppe RNF4 interacts with both SUMO and nucleosomes to promote the DNA damage response.
ChainB
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN B C136 C139 C163 C166 C9 C12 C36 C39
BS02 ZN B C158 H160 C177 C180 C31 H33 C50 C53
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding

View graph for
Molecular Function
External links
PDB RCSB:4ppe, PDBe:4ppe, PDBj:4ppe
PDBsum4ppe
PubMed24714598
UniProtP78317|RNF4_HUMAN E3 ubiquitin-protein ligase RNF4 (Gene Name=RNF4)

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