Structure of PDB 4pc6 Chain B

Receptor sequence
>4pc6B (length=368) Species: 316385 (Escherichia coli str. K-12 substr. DH10B) [Search protein sequence]
TKPHVNVGTIGHVDHGKTTLTAAITTVLAKTYGGKARGISHVEYDTPTRH
YAHVDCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLGRQV
GVPYIIVFLNKCDMVDDEELLELVEMEVRELLSQYDFPGDDTPIVRGSAL
KALEGDAEWEAKILELAGFLDSYIPEPERAIDKPFLLPIEDVFSISGRGT
VVTGRVERGIIKVGEEVEIVGIKETQKSTCTGVEMFRKLLDEGRAGENVG
VLLRGIKREEIERGQVLAKPGTIKPHTKFESEVYILSKDEGGRHTPFFKG
YRPQFYFRTTDVTGTIELPEGVEMVMPGDNIKMVVTLIHPIAMDDGLRFA
IREGGRTVGAGVVAKVLG
3D structure
PDB4pc6 Structural outline of the detailed mechanism for elongation factor Ts-mediated guanine nucleotide exchange on elongation factor Tu.
ChainB
Resolution2.2 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H22 K24 T25 H84
Catalytic site (residue number reindexed from 1) H15 K17 T18 H59
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GNP B V20 G23 K24 T25 T26 N135 K136 D138 S173 A174 L175 V13 G16 K17 T18 T19 N110 K111 D113 S148 A149 L150
Gene Ontology
Molecular Function
GO:0003746 translation elongation factor activity
GO:0003924 GTPase activity
GO:0005525 GTP binding
GO:0097216 guanosine tetraphosphate binding
Biological Process
GO:0006412 translation
GO:0006414 translational elongation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Biological Process
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Cellular Component
External links
PDB RCSB:4pc6, PDBe:4pc6, PDBj:4pc6
PDBsum4pc6
PubMed26073967
UniProtA0A0M3KKV1

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