Structure of PDB 4p7s Chain B

Receptor sequence
>4p7sB (length=100) Species: 5833 (Plasmodium falciparum) [Search protein sequence]
PCCEVITNVNLPDDNVQSTLSQIENAISDVKPLGYIMSNYDYQKNLRFGG
SNEAYCFVRITSINNSALADQITKLLVSNLNVKSRRIYVEFRDCNFAFGS
3D structure
PDB4p7s Crystallographic and Receptor Binding Characterization of Plasmodium falciparum Macrophage Migration Inhibitory Factor Complexed to Two Potent Inhibitors.
ChainB
Resolution2.87 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 5.3.2.1: phenylpyruvate tautomerase.
5.3.3.12: L-dopachrome isomerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 2OK B P1 Y37 N106 F107 P1 Y35 N95 F96 PDBbind-CN: -logKd/Ki=7.42,Ki=38nM
BS02 2OK B F50 Y57 F48 Y55 PDBbind-CN: -logKd/Ki=7.42,Ki=38nM
Gene Ontology
Molecular Function
GO:0005125 cytokine activity
GO:0050178 phenylpyruvate tautomerase activity
Biological Process
GO:0007165 signal transduction
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4p7s, PDBe:4p7s, PDBj:4p7s
PDBsum4p7s
PubMed25268646
UniProtQ6Q3H7

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