Structure of PDB 4p42 Chain B

Receptor sequence
>4p42B (length=431) Species: 9606 (Homo sapiens) [Search protein sequence]
TERAEWLNKTVKHMWPFICQFIEKLFRETIEPAVRGANTHLSTFSFTKVD
VGQQPLRINGVKVYTKRQIILDLQISFVGNCEIDLEIKRYFCRAGVKSIQ
IHGTMRVILEPLIGDMPLVGALSIFFLRKPLLEINWTGLTNLLDVPGLNG
LSDTIILDIISNYLVLPNRITVPLVSRFPVPKGVLRIHFIEAQDLPYGII
RVGNQIFQSRVIKENLSPKWNEVYEALVYEHPGQELEIELFDEDPDDFLG
SLMIDLIEVEKERLLDEWFTLDEVPKGKLHLRLEWLTLMPNASNLDKVLT
DIKAGLSSALLILYLDSARNLPSGKKISSNPNPVVQMSVGHKAQESKIRY
KTNEPVWEENFTFFIHNPKRQDLEVEVRDEQHQCSLGNLKVPLSQLLTSE
DMTVSQRFQLSNSGPNSTIKMKIALRVLHLE
3D structure
PDB4p42 Structure of a lipid-bound extended synaptotagmin indicates a role in lipid transfer.
ChainB
Resolution2.44 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 EGC B Y330 L331 N335 R336 Y163 L164 N168 R169
Gene Ontology
Biological Process
GO:0006869 lipid transport
GO:0061817 endoplasmic reticulum-plasma membrane tethering

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Molecular Function
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Biological Process
External links
PDB RCSB:4p42, PDBe:4p42, PDBj:4p42
PDBsum4p42
PubMed24847877
UniProtA0FGR8|ESYT2_HUMAN Extended synaptotagmin-2 (Gene Name=ESYT2)

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