Structure of PDB 4ozq Chain B

Receptor sequence
>4ozqB (length=687) Species: 1281237 (Escherichia coli UMEA 3304-1) [Search protein sequence]
EEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVAA
TGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTWDAVRYNGK
LIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQ
EPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNK
HMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTFKG
QPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAV
ALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAAS
GRQTVDAALAAAQTNAAAENSQVTVAVRVRPFSKREKTEKASQVVFTNGE
EITVEHPDMKQVYSFIYDVSFWSFDECHPGYASQTTVYETLAAPLLDRAF
EGYNTCLFAYGQTGSGKSYTMMGLNEEPGIIPRFCEDLFAQIAKKQTSEV
SYHLEMSFFEVYNEKIHDLLVCKQPLRAREHPVSGPYVEGLSMNVVSSYS
DIQSWLELGNKQRATADKSSRSHSVFTLVMTQTKTDHRITSRINLVDLAG
SERCGQRLKEGVSINKSLLTLGKVISALSEQANGKRVFIPYRESTLTWLL
KESLGGNSKTAMIATVSPAASNIEETLSTLRYATQAR
3D structure
PDB4ozq KIF14 binds tightly to microtubules and adopts a rigor-like conformation.
ChainB
Resolution2.71 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ADP B R399 R401 P402 T484 G485 G487 K488 S489 Y490 R378 R380 P381 T463 G464 G466 K467 S468 Y469
Gene Ontology
Molecular Function
GO:0003777 microtubule motor activity
GO:0005524 ATP binding
GO:0008017 microtubule binding
GO:0015144 carbohydrate transmembrane transporter activity
Biological Process
GO:0007018 microtubule-based movement
GO:0008643 carbohydrate transport
GO:0055085 transmembrane transport

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:4ozq, PDBe:4ozq, PDBj:4ozq
PDBsum4ozq
PubMed24949858
UniProtL0N7N1|KIF14_MOUSE Kinesin-like protein KIF14 (Gene Name=Kif14)

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