Structure of PDB 4ozi Chain B

Receptor sequence
>4oziB (length=180) Species: 9606 (Homo sapiens) [Search protein sequence]
SPEDFVYQFKGMCYFTNGTERVRLVSRSIYNREEIVRFDSDVGEFRAVTL
LGLPAAEYWNSQKDILERKRAAVDRVCRHNYQLELRTTLQRRVEPTVTIS
PHNLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTPLIRNGDWTFQILVM
LEMTPQRGDVYTCHVEHPSLQSPITVEWRA
3D structure
PDB4ozi T-cell receptor recognition of HLA-DQ2-gliadin complexes associated with celiac disease.
ChainB
Resolution3.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide B Y9 F11 G13 L26 S30 L53 P56 A57 Y60 W61 I67 R77 V78 H81 N82 Y7 F9 G11 L24 S28 L51 P54 A55 Y58 W59 I65 R75 V76 H79 N80
BS02 CA B E96 S179 Q181 E94 S169 Q171
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:4ozi, PDBe:4ozi, PDBj:4ozi
PDBsum4ozi
PubMed24777060
UniProtQ5Y7D3

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