Structure of PDB 4or2 Chain B

Receptor sequence
>4or2B (length=366) Species: 562,9606 [Search protein sequence]
DLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDAQKATPPKLEDK
SPDSPEMKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNAY
IQKYLIPVRYLEWSNIESIIAIAFSCLGILVTLFVTLIFVLYRDTPVVKS
SSRELCYIILAGIFLGYVCPFTLIAKPTTTSCYLQRLLVGLSSAMCYSAL
VTKTNRIARILAGCTRKPRFMSAWAQVIIASILISVQLTLVVTLIIMEPP
MPILSYPSIKEVYLICNTSNLGVVAPLGYNGLLIMSCTYYAFKTRNVPAN
FNEAKYIAFTMYTTCIIWLAFVPIYFGSNYKIITTCFAVSLSVTVALGCM
FTPKMYIIIAKPERNV
3D structure
PDB4or2 Structure of a class C GPCR metabotropic glutamate receptor 1 bound to an allosteric modulator
ChainB
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CLR B W588 F646 W113 F171
BS02 FM9 B Q660 V664 P756 L757 N760 T794 I797 W798 K811 I812 T815 S822 Q185 V189 P276 L277 N280 T314 I317 W318 K331 I332 T335 S342
BS03 CLR B I594 A598 C601 I119 A123 C126
BS04 CLR B V643 T647 T653 T655 L659 V168 T172 T178 T180 L184
Gene Ontology
Molecular Function
GO:0004930 G protein-coupled receptor activity
GO:0005506 iron ion binding
GO:0009055 electron transfer activity
GO:0020037 heme binding
GO:0046872 metal ion binding
Biological Process
GO:0007186 G protein-coupled receptor signaling pathway
GO:0022900 electron transport chain
Cellular Component
GO:0016020 membrane
GO:0042597 periplasmic space

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Biological Process
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Cellular Component
External links
PDB RCSB:4or2, PDBe:4or2, PDBj:4or2
PDBsum4or2
PubMed24603153
UniProtP0ABE7|C562_ECOLX Soluble cytochrome b562 (Gene Name=cybC);
Q13255|GRM1_HUMAN Metabotropic glutamate receptor 1 (Gene Name=GRM1)

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