Structure of PDB 4oni Chain B

Receptor sequence
>4oniB (length=242) Species: 9606 (Homo sapiens) [Search protein sequence]
SIPHLILELLKCEPDEPQVQAKIMAYLQQEQANRSKHEKLSTFGLMCKMA
DQTLFSIVEWARSSIFFRELKVDDQMKLLQNCWSELLILDHIYRQVVHGK
EGSIFLVTGQQVDYSIIASQAGATLNNLMSHAQELVAKLRSLQFDQREFV
CLKFLVLFSLDVKNLENFQLVEGVQEQVNAALLDYTMCNYPQQTEKFGQL
LLRLPEIRAISMQAEEYLYYKHLNGDVPYNNLLIEMLHAKRA
3D structure
PDB4oni Human nuclear receptor LRH1 bound to phosopholipids and SHP peptide
ChainB
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B F354 R361 V371 M375 Q379 N530 E534 F55 R62 V72 M76 Q80 N231 E235
BS02 P6L B F342 M345 L386 H390 Q419 A420 G421 L424 M428 A513 Y516 K520 F43 M46 L87 H91 Q120 A121 G122 L125 M129 A214 Y217 K221
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity

View graph for
Molecular Function
External links
PDB RCSB:4oni, PDBe:4oni, PDBj:4oni
PDBsum4oni
PubMed
UniProtO00482|NR5A2_HUMAN Nuclear receptor subfamily 5 group A member 2 (Gene Name=NR5A2)

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