Structure of PDB 4omk Chain B

Receptor sequence
>4omkB (length=274) Species: 9606 (Homo sapiens) [Search protein sequence]
MSGRVGDLSPRQKEALAKFRENVQDVLPALPNPDDYFLLRWLRARSFDLQ
KSEAMLRKHVEFRKQKDIDNIISWQPPEVIQQYLSGGMCGYDLDGCPVWY
DIIGPLDAKGLLFSASKQDLLRTKMRECELLLQECAHQTTKLGRKVETIT
IIYDCEGLGLKHLWKPAVEAYGEFLCMFEENYPETLKRLFVVKAPKLFPV
AYNLIKPFLSEDTRKKIMVLGANWKEVLLKHISPDQVPVEYGGTMTDPDG
NPKCKSKINYGGDIPRKYYVRDQV
3D structure
PDB4omk Structural insights on cholesterol endosynthesis: Binding of squalene and 2,3-oxidosqualene to supernatant protein factor.
ChainB
Resolution1.75 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SQL B A108 L111 K124 Y153 H162 A170 L175 L189 A201 Y202 A108 L111 K124 Y153 H162 A170 L175 L189 A201 Y202 MOAD: Kd=40.1uM
External links
PDB RCSB:4omk, PDBe:4omk, PDBj:4omk
PDBsum4omk
PubMed25987292
UniProtO76054|S14L2_HUMAN SEC14-like protein 2 (Gene Name=SEC14L2)

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