Structure of PDB 4oj8 Chain B

Receptor sequence
>4oj8B (length=271) Species: 555 (Pectobacterium carotovorum subsp. carotovorum) [Search protein sequence]
SEIVKFNPVMASGFGAYIDHRDFLEAKTETIKNLLMRQGFVVVKNLDIDS
DTFRDIYSAYGTIVEYADEKIGVGFGYRDTLKLEGEKGKIVTGRGQLPFH
ADGGLLLSQVDQVFLYAAEIKNVKFRGATTVCDHALACQEMPAHLLRVLE
EETFEVRVLERGYYVDVSPDGWFKVPVFTDLGWVRKMLIYFPFDEGQPAS
WEPRIVGFTDHETQAFFQELGAFLKQPRYYYKHFWEDGDLLIMDNRRVIH
EREEFNDDDIVRRLYRGQTAD
3D structure
PDB4oj8 Mechanism of the C5 stereoinversion reaction in the biosynthesis of carbapenem antibiotics.
ChainB
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.14.20.3: (5R)-carbapenem-3-carboxylate synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FE2 B H101 D103 H251 H100 D102 H250
BS02 AKG B L84 L98 H101 H251 R253 R263 R267 L83 L97 H100 H250 R252 R262 R266
BS03 2TQ B D103 G104 L106 L107 Y164 R267 Q269 D102 G103 L105 L106 Y163 R266 Q268
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
GO:0051213 dioxygenase activity
Biological Process
GO:0017000 antibiotic biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Biological Process
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Cellular Component
External links
PDB RCSB:4oj8, PDBe:4oj8, PDBj:4oj8
PDBsum4oj8
PubMed24604200
UniProtQ9XB59|CARC_PECCC (5R)-carbapenem-3-carboxylate synthase (Gene Name=carC)

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