Structure of PDB 4ofn Chain B

Receptor sequence
>4ofnB (length=205) Species: 51031 (Necator americanus) [Search protein sequence]
VHYKLTYFAIRGAGECARQIFALADQEFEDVRLDKEQFAKVKPDLPFGQV
PVLEVDGKQLAQSLAICRYLARQFGFAGKSTFDEAVVDSLADQYSDYRVE
IKSFFYTVIGMREGDVEQLKKEVLLPARDKFFGFITKFLKKSPSGFLVGD
SLTWVDLLVSEHNATMLTFVPEFLEGYPEVKEHMEKIRAIPKLKKWIETR
PETLF
3D structure
PDB4ofn Structure of glutathione S-transferase 1 from the major human hookworm parasite Necator americanus (Na-GST-1) in complex with glutathione.
ChainB
Resolution2.69 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) Y8 A14 R19 V109
Catalytic site (residue number reindexed from 1) Y7 A13 R18 V108
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GSH B F9 F39 Q50 V51 Q63 S64 F8 F38 Q49 V50 Q62 S63
Gene Ontology
Molecular Function
GO:0004364 glutathione transferase activity
GO:0016740 transferase activity
Biological Process
GO:0006749 glutathione metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:4ofn, PDBe:4ofn, PDBj:4ofn
PDBsum4ofn
PubMed25195885
UniProtD3U1A5

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