Structure of PDB 4nvk Chain B

Receptor sequence
>4nvkB (length=289) Species: 285006 (Saccharomyces cerevisiae RM11-1a) [Search protein sequence]
LVHVASVEKGRSYEDFQKVYNAIALKLREDDEYDNYIGYGPVLVRLAWHI
SGTWDKHDNTGGSYGGTYRFKKEFNDPSNAGLQNGFKFLEPIHKEFPWIS
SGDLFSLGGVTAVQEMQGPKIPWRCGRVDTPEDTTPDNGRLPDADKDAGY
VRTFFQRLNMNDREVVALMGAHALGKTHLKNSGYEGGGANNVFTNEFYLN
LLNEDWKLEKNDANNEQWDSKSGYMMLPTDYSLIQDPKYLSIVKEYANDQ
DKFFKDFSKAFEKLLENGITFPKDAPSPFIFKTLEEQGL
3D structure
PDB4nvk Incorporation of protein flexibility and conformational energy penalties in docking screens to improve ligand discovery.
ChainB
Resolution1.56 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.11.1.-
1.11.1.5: cytochrome-c peroxidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HEM B P44 R48 W51 D146 A147 L171 M172 A174 H175 G178 K179 T180 H181 N184 S185 L230 P41 R45 W48 D143 A144 L168 M169 A171 H172 G175 K176 T177 H178 N181 S182 L227
BS02 2NY B H175 G178 K179 T180 G191 A192 N203 M228 D233 H172 G175 K176 T177 G188 A189 N200 M225 D230
Gene Ontology
Molecular Function
GO:0004601 peroxidase activity
GO:0020037 heme binding
Biological Process
GO:0006979 response to oxidative stress
GO:0034599 cellular response to oxidative stress

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Molecular Function
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Biological Process
External links
PDB RCSB:4nvk, PDBe:4nvk, PDBj:4nvk
PDBsum4nvk
PubMed24950326
UniProtB3LRE1

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