Structure of PDB 4nnr Chain B

Receptor sequence
>4nnrB (length=101) Species: 9606 (Homo sapiens) [Search protein sequence]
CPIKSRKGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQ
GLLGMCEGEKRKLVIPSELGYGERGAPPKIPGGATLVFEVELLKIERRTE
L
3D structure
PDB4nnr Atomic structure of the Immunophilin FKBP13-FK506 Complex: Insights into the Composite Binding Surface for Calcineurin
ChainB
Resolution1.98 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) Y56 F66 D67 I86 Y112 F129
Catalytic site (residue number reindexed from 1) Y15 F25 D26 I45 Y71 F88
Enzyme Commision number 5.2.1.8: peptidylprolyl isomerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FK5 B Y56 D67 F76 V85 W89 Y112 F129 Y15 D26 F35 V44 W48 Y71 F88
Gene Ontology
Molecular Function
GO:0003755 peptidyl-prolyl cis-trans isomerase activity
Biological Process
GO:0000413 protein peptidyl-prolyl isomerization
GO:0061077 chaperone-mediated protein folding

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Molecular Function
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Biological Process
External links
PDB RCSB:4nnr, PDBe:4nnr, PDBj:4nnr
PDBsum4nnr
PubMed
UniProtP26885|FKBP2_HUMAN Peptidyl-prolyl cis-trans isomerase FKBP2 (Gene Name=FKBP2)

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