Structure of PDB 4nms Chain B

Receptor sequence
>4nmsB (length=87) Species: 9606 (Homo sapiens) [Search protein sequence]
GPIRKVLLLKEDHEGLGISITGGKEHGVPILISEIHPGQPADRCGGLHVG
DAILAVNGVNLRDTKHKEAVTILSQQRGEIEFEVVYV
3D structure
PDB4nms Chemically Modified Peptide Scaffolds Target the CFTR-Associated Ligand PDZ Domain.
ChainB
Resolution1.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B I286 P312 R345 V368 I3 P29 R62 V85
BS02 peptide B G298 L299 G300 I301 S302 I303 T304 H309 V311 E317 H349 V353 L356 G15 L16 G17 I18 S19 I20 T21 H26 V28 E34 H66 V70 L73
Gene Ontology
Cellular Component
GO:0005794 Golgi apparatus

View graph for
Cellular Component
External links
PDB RCSB:4nms, PDBe:4nms, PDBj:4nms
PDBsum4nms
PubMed25136860
UniProtQ9HD26|GOPC_HUMAN Golgi-associated PDZ and coiled-coil motif-containing protein (Gene Name=GOPC)

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