Structure of PDB 4nmn Chain B

Receptor sequence
>4nmnB (length=412) Species: 224324 (Aquifex aeolicus VF5) [Search protein sequence]
PCDESAERAVLGSMLEDPENIPLVLEYLKEEDFCIDEHKLLFRVLTNLWS
EGNKLDFVLIKDHLEKKPIDWLEELYEEAVSPDTLEEVCKIVKQRSAQRA
IIQLGIELIHKGKENKDFHTLIEEAQSRIFSIAESATSTQFYHVKDVAEE
VIELIYKFKSSDRLVTGLPSGFTELDLKTTGFHPGDLIILAARPGMGKTA
FMLSIIYNLAKDEGKPSAVFSLEMSKEQLVMRLLSMMSEVPLFKIRSGSI
SNEDLKKLEASAIELAKYDIYLDDTPALTTTDLRIRARKLRKEKEVEFVA
VDYLQLLRPPVRKSPRQEEVAEVSRNLKALAKELRIPVMALAQLSKRPQL
ADLRESGQIEQDADLILFLHRPEYYTPEEQGIAEVIIAKQRQGPTDIVKL
AFIKEYTKFANL
3D structure
PDB4nmn Nucleotide and partner-protein control of bacterial replicative helicase structure and function.
ChainB
Resolution3.301 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.12: DNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP B R417 Q418 R391 Q392
BS02 ADP B G209 G211 K212 T213 A214 R246 K430 T433 G195 G197 K198 T199 A200 R232 K404 T407
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0004386 helicase activity
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
GO:0046872 metal ion binding
Biological Process
GO:0006260 DNA replication
GO:0006268 DNA unwinding involved in DNA replication
GO:0006269 DNA replication, synthesis of primer
GO:0032508 DNA duplex unwinding
Cellular Component
GO:0005829 cytosol
GO:1990077 primosome complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4nmn, PDBe:4nmn, PDBj:4nmn
PDBsum4nmn
PubMed24373746
UniProtO67450

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