Structure of PDB 4nmc Chain B

Receptor sequence
>4nmcB (length=969) Species: 243231 (Geobacter sulfurreducens PCA) [Search protein sequence]
NSELNTKIVNRGKEFFGSISGEKPSLFNKGAWMGKAMDWSMQNEQFKIQM
FRFVDVFPSLTTSKLLTEHIREYFGGGAVLNKVLTSNIEEMARQFIVGET
TKEAVKNLEKLRKDGFAAVVDVLGEATLSEEEAEVYTNTYLELLEALKKE
QGSWKGLPGKGGDPGLDWGHAPKVNIAVKPTALFCLANPQDFEGSVVAIL
DRMRRIFKKVMELNGFLCIDMESYRHKEIILEVFRRLKLEYRDYPHLGIV
LQAYLKDNDKDLDDLLAWAKEHKVQISVRLVKGAYWDYETVKAKQNDWEV
PVWTIKAESDAAYERQARKILENHQICHFACASHNIRTISAVMEMARELN
VPEDRYEFQVLYGMAEPVRKGILKVAGRIRLYAPYGNMVPGMGYLVRRLL
ENTANESFLRQSFAEDAQIERLLEDPAVTVERERAARAGLGGLPPFNNEA
MVDFTRADHRAAFPKHIAQVRTQLGKTYPLFINGKEVRTNDLIPTVNPNK
PSEVLGQICQAGTTEVGDAIAAAKAAFPAWRDTDPRTRAEYLLKAAQAAR
KRLFELSAWQVLEIGKQWDQAYADVTEAIDFLEYYAREMIRLGQPQRVGH
APGELNHYFYEPKGVAAVIAPWNFPLAISMGMASAAIVTGNCVVFKPSGI
TSIIGWHLVELFREAGLPEGVFNFTPGRGSVMGDYLVDHPDISLIAFTGS
METGLRIIERAAKVHPGQANVKKIISEMGGKNAIIIDDDADLDEAVPHVL
YSAFGFQGQKCSACSRVIVLDAVYDKFIERLVSMAKATKVGPSEDPANYM
GAVADDKAMKSIKEYAEIGKREGHVLYESPVPAGEGYFVPMTIIGGIKPE
HRIAQEEIFGPVLAVMRAKDFDQAIEWANSTQFALTGGIFSRSPEHLAKA
RREFRVGNLYINRNNTGALVERQPFGGARMSGVGTKAGGPDYLLHFMDPR
VVTENTMRRGFAPIEEDDD
3D structure
PDB4nmc Structures of the PutA peripheral membrane flavoenzyme reveal a dynamic substrate-channeling tunnel and the quinone-binding site.
ChainB
Resolution1.901 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) N655 K678 E759 C793 E889 A969
Catalytic site (residue number reindexed from 1) N623 K646 E727 C761 E857 A937
Enzyme Commision number 1.2.1.88: L-glutamate gamma-semialdehyde dehydrogenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FAD B D244 M245 V274 Q276 R303 V305 K306 G307 A308 Y309 W310 W327 T328 I329 K330 S333 A356 S357 H358 N359 L385 E425 S431 F432 D220 M221 V250 Q252 R279 V281 K282 G283 A284 Y285 W286 W303 T304 I305 K306 S309 A332 S333 H334 N335 L361 E401 S407 F408
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003700 DNA-binding transcription factor activity
GO:0003842 1-pyrroline-5-carboxylate dehydrogenase activity
GO:0004657 proline dehydrogenase activity
GO:0016491 oxidoreductase activity
GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006562 proline catabolic process
GO:0010133 proline catabolic process to glutamate
Cellular Component
GO:0005737 cytoplasm
GO:0009898 cytoplasmic side of plasma membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4nmc, PDBe:4nmc, PDBj:4nmc
PDBsum4nmc
PubMed24550478
UniProtQ746X3

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