Structure of PDB 4nl8 Chain B

Receptor sequence
>4nl8B (length=566) Species: 272620 (Klebsiella pneumoniae subsp. pneumoniae MGH 78578) [Search protein sequence]
VAHVALPVPLPRTFDYLLPEKAGCRVRVPFGKQERIGIVAAVLKPVAELD
DEPVFSTTVWRLLMWAAEYYHHPIGDVLFHALPVMLRQGKPASALRLNTE
QATAVGAIHSAADRFSAWLLAGITGSGKTEVYLSVLENVLAQGRQALVMV
PEIGLTPQTIARFRQRFNAPVEVLHSGLNDSERLSAWLKAKNGEAAIVIG
TRSSLFTPFKDLGVIVIDEEHDSSYKQQEGWRYHARDLAVWRAHSEQIPI
ILGSATPALETLHNVRQGKYRQLTLQQHVLDLKGQPLQAGLSPALISRMR
QHLQADNQVILFLNRRGFAPALLCHDCGWIAECPRCDSYYTLHQAQHHLR
CHHCDSQRPIPRQCPSCGSTHLVPVGIGTEQLEQALAPLFPGGARILIGT
QMLAKGHHFPDVTLVSLLDVDGALFSADFRSAERFAQLYTQVSGRAGEVI
LQTHHPEHPLLQTLLYKGYDAFAEQALAERQTMQLPPWTSHVLIRANNQQ
APLFLQQLRNLLQASPLADEKLWVLGPVPALAWQILLQHPSRVRLQHIVS
GTLALIWVLDVDPIEG
3D structure
PDB4nl8 Structural mechanisms of PriA-mediated DNA replication restart.
ChainB
Resolution4.08 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.6.4.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B V341 V698 V240 V543
BS02 ZN B C435 C438 C475 C478 C324 C327 C364 C367
BS03 ZN B C444 C447 C462 C465 C333 C336 C351 C354
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0004386 helicase activity
GO:0005524 ATP binding
GO:0008270 zinc ion binding
GO:0016787 hydrolase activity
GO:0043138 3'-5' DNA helicase activity
GO:0046872 metal ion binding
Biological Process
GO:0006260 DNA replication
GO:0006268 DNA unwinding involved in DNA replication
GO:0006269 DNA replication, synthesis of primer
GO:0006270 DNA replication initiation
GO:0006302 double-strand break repair
GO:0006310 DNA recombination
GO:0032508 DNA duplex unwinding
Cellular Component
GO:1990077 primosome complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4nl8, PDBe:4nl8, PDBj:4nl8
PDBsum4nl8
PubMed24379377
UniProtA6TGC5

[Back to BioLiP]