Structure of PDB 4nib Chain B

Receptor sequence
>4nibB (length=30) Species: 9606 (Homo sapiens) [Search protein sequence]
FVNQHLCGSHLVEALYLVCAERAFFYTPKT
3D structure
PDB4nib Protective hinge in insulin opens to enable its receptor engagement.
ChainB
Resolution1.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B V2 N3 Q4 H5 L6 C7 L11 L15 V18 C19 R22 A23 F24 F25 P28 V2 N3 Q4 H5 L6 C7 L11 L15 V18 C19 R22 A23 F24 F25 P28
Gene Ontology
Molecular Function
GO:0005179 hormone activity
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Cellular Component
External links
PDB RCSB:4nib, PDBe:4nib, PDBj:4nib
PDBsum4nib
PubMed25092300
UniProtP01308|INS_HUMAN Insulin (Gene Name=INS)

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