Structure of PDB 4nf5 Chain B

Receptor sequence
>4nf5B (length=273) Species: 10116 (Rattus norvegicus) [Search protein sequence]
NHLSIVTLEEAPFVIVEDICVRNTVPCRKFVKINNSTNEGMNVKKCCKGF
CIDILKKLSRTVKFTYDLYLVTNGKHGKKVNNVWNGMIGEVVYQRAVMAV
GSLTINEERSEVVDFSVPFVETGISVMVSRGTQVTGLSDKKFQRPHDYSP
PFRFGTVPNGSTERNIRNNYPYMHQYMTRFNQRGVEDALVSLKTGKLDAF
IYDAAVLNYKAGRDEGCKLVTIGSGYIFATTGYGIALQKGSPWKRQIDLA
LLQFVGDGEMEELETLWLTGICH
3D structure
PDB4nf5 Structural Insights into Competitive Antagonism in NMDA Receptors.
ChainB
Resolution1.903 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 2JJ B H88 S114 L115 T116 R121 G172 S173 T174 Y214 H76 S102 L103 T104 R109 G160 S161 T162 Y202 BindingDB: Ki=390nM
Gene Ontology
Molecular Function
GO:0015276 ligand-gated monoatomic ion channel activity
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:4nf5, PDBe:4nf5, PDBj:4nf5
PDBsum4nf5
PubMed24462099
UniProtQ00959|NMDE1_RAT Glutamate receptor ionotropic, NMDA 2A (Gene Name=Grin2a)

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