Structure of PDB 4ncl Chain B

Receptor sequence
>4nclB (length=435) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence]
NLRSPICCILGHVDTGKTKLLDKIRQTGGITQQIGATYFPVEAIKQKTAV
VNKDGKFEFKVPGLLIIDTPGHESFSNLRSRGSSLCNIAILVVDIMHGLE
PQTIESLRLLRERKTPFVVALNKIDRLYGWKKIENNGFRESFALQNKAVQ
NEFRNRLDQVKLQFAEQGFNSELFYENKNFARYVSLVPTSAHTGEGIPDM
LKLIVQLCQERMASSLMYLSELQATVLEVKAIEGFGVTIDVILSNGILRE
GDRIVLCGLEGPIKTNIRALLTPAPGQYIHHKEVKAAQGVKISAPGLEGA
IAGSRLLVVGPDDDEEELEEEVESDLQSLFSRVEKTGKGVSVQASTLGSL
EALLDFLKDCKIPVANVGIGPVYKRDVMQCGIMLEKAPDYAVMLCFDVKV
DKEAQQYADENGIKIFTADIIYHLFDQFTKHMQEQ
3D structure
PDB4ncl eIF5B employs a novel domain release mechanism to catalyze ribosomal subunit joining.
ChainB
Resolution2.115 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.5.3: protein-synthesizing GTPase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GDP B D533 T534 G535 K536 T537 K538 N648 K649 D651 S716 A717 H718 D14 T15 G16 K17 T18 K19 N122 K123 D125 S190 A191 H192
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding

View graph for
Molecular Function
External links
PDB RCSB:4ncl, PDBe:4ncl, PDBj:4ncl
PDBsum4ncl
PubMed24686316
UniProtG0S8G9|IF2P_CHATD Eukaryotic translation initiation factor 5B (Gene Name=CTHT_0029840)

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