Structure of PDB 4ncf Chain B

Receptor sequence
>4ncfB (length=429) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
KDLRSPICCILGHVDTGKTKLLDKIRQTGITQQIGATYFPIDAIKAKTKV
MAEYEKQTFDVPGLLVIDTPNLRSRGSSLCNIAILVIDIMHGLEQQTIES
IKLLRDRKAPFVVALNKIDRLYDWKAIPNNSFRDSFAKQSRAVQEEFQSR
YSKIQLELAEQGLNSELYFQNKNMSKYVSIVPTSAVTGEGVPDLLWLLLE
LTQKRMSKQLMYLSHVEATILEVKVVEGFGTTIDVILSNGYLREGDRIVL
CGMNGPIVTNIRALLTPQPLRELRLKSEYVHHKEVKAALGVKIAANDLEK
AVSGSRLLVVGPEDDEDELMDDVMDDLTGLLDSKGVVVQASTLGSLEALL
DFLKDMKIPVMSIGLGPVYKRDVMKASTMLEKAPEYAVMLCFDVKVDKEA
EQYAEQEGIKIFNADVIYHLFDSFTAYQE
3D structure
PDB4ncf eIF5B employs a novel domain release mechanism to catalyze ribosomal subunit joining.
ChainB
Resolution3.015 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.6.5.3: protein-synthesizing GTPase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GDP B V414 D415 G417 K418 T419 K420 N530 K531 D533 R534 S598 A599 V600 V14 D15 G17 K18 T19 K20 N116 K117 D119 R120 S184 A185 V186
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding

View graph for
Molecular Function
External links
PDB RCSB:4ncf, PDBe:4ncf, PDBj:4ncf
PDBsum4ncf
PubMed24686316
UniProtP39730|IF2P_YEAST Eukaryotic translation initiation factor 5B (Gene Name=FUN12)

[Back to BioLiP]