Structure of PDB 4nb3 Chain B

Receptor sequence
>4nb3B (length=122) Species: 9606 (Homo sapiens) [Search protein sequence]
SHMVGQLSRGAIAAIMQKGDTNIKPILQVINIRPITTGNSPPRYRLLMSD
GLNTLSSFMLATQLNPLVEEEQLSSNCVCQIHRFIVNTLKDGRRVVILME
LEVLKSAEAVGVKIGNPVPYNE
3D structure
PDB4nb3 Discovery of a Potent Stapled Helix Peptide That Binds to the 70N Domain of Replication Protein A.
ChainB
Resolution1.35 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide B S-1 H0 V2 R7 S1 H2 V4 R9
BS02 peptide B I33 T35 R41 R43 F56 M57 T60 I83 N85 L87 K88 R91 I35 T37 R43 R45 F58 M59 T62 I85 N87 L89 K90 R93
Gene Ontology
Biological Process
GO:0006260 DNA replication
Cellular Component
GO:0005634 nucleus

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:4nb3, PDBe:4nb3, PDBj:4nb3
PDBsum4nb3
PubMed24491171
UniProtP27694|RFA1_HUMAN Replication protein A 70 kDa DNA-binding subunit (Gene Name=RPA1)

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