Structure of PDB 4mxe Chain B

Receptor sequence
>4mxeB (length=177) Species: 9606 (Homo sapiens) [Search protein sequence]
LYFQSMKKERILAEYPDGRIIMVLPEDPKYALKKVDEIREMVDNSRTKTL
LFISNDKKVVGCLIAEHIQWGYRVIEEKLPVIRSEEEKVRFERQKAWCCS
TLPEPAICGISRIWVFSMMRRKKIASRMIECLRSNFIYGSYLSKEEIAFS
DPTPDGKLFATQYCGTGQFLVYNFING
3D structure
PDB4mxe Sister Chromatid Cohesion Establishment Factor ESCO1 Operates by Substrate-Assisted Catalysis.
ChainB
Resolution2.6 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.3.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ACO B I772 V774 R779 R780 K782 A784 S785 S809 T812 D814 L817 F818 Q821 I113 V115 R120 R121 K123 A125 S126 S150 T153 D155 L158 F159 Q162
External links
PDB RCSB:4mxe, PDBe:4mxe, PDBj:4mxe
PDBsum4mxe
PubMed27112597
UniProtQ5FWF5|ESCO1_HUMAN N-acetyltransferase ESCO1 (Gene Name=ESCO1)

[Back to BioLiP]