Structure of PDB 4mtz Chain B

Receptor sequence
>4mtzB (length=77) Species: 9606 (Homo sapiens) [Search protein sequence]
EFVEEFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVD
RWQYGDSAVGRHRKVSPNCRFINGFYL
3D structure
PDB4mtz Protein-protein interactions in nfkb pathway: novel tools to promote apoptosis in cancer therapy
ChainB
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN B C1063 C1066 H1083 C1090 C42 C45 H62 C69
BS02 0BU B R1062 C1066 H1067 S1087 P1088 N1089 R41 C45 H46 S66 P67 N68
External links
PDB RCSB:4mtz, PDBe:4mtz, PDBj:4mtz
PDBsum4mtz
PubMed
UniProtP98170|XIAP_HUMAN E3 ubiquitin-protein ligase XIAP (Gene Name=XIAP)

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