Structure of PDB 4mtt Chain B

Receptor sequence
>4mttB (length=127) Species: 208964 (Pseudomonas aeruginosa PAO1) [Search protein sequence]
MRILHSMLRVADLEAALEFYTRALDMRLLRRRDYPEGRFTLAFVGYQDER
AAAALELTHNWDRDGYTQGDGYGHLAIEVEDAAVTCARARALGYRVTREA
GLMQHGRSVIAFLEDPDGYKVELIQKG
3D structure
PDB4mtt The crystal structure of a homodimeric Pseudomonas glyoxalase I enzyme reveals asymmetric metallation commensurate with half-of-sites activity.
ChainB
Resolution2.17 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H5 E56 H74 E122
Catalytic site (residue number reindexed from 1) H5 E56 H74 E122
Enzyme Commision number 4.4.1.5: lactoylglutathione lyase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN B H74 E122 H74 E122
BS02 ZN B H105 E122 H105 E122
Gene Ontology
Molecular Function
GO:0004462 lactoylglutathione lyase activity
GO:0016829 lyase activity
GO:0046872 metal ion binding
Biological Process
GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione
Cellular Component
GO:0005737 cytoplasm

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External links
PDB RCSB:4mtt, PDBe:4mtt, PDBj:4mtt
PDBsum4mtt
PubMed25411134
UniProtQ9I5L8

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