Structure of PDB 4mtl Chain B

Receptor sequence
>4mtlB (length=219) Species: 9606 (Homo sapiens) [Search protein sequence]
SNKIEPSLHSLQKFVPTDYASYTQEHYRFAGKEIVIQESIESYGAVVWPG
AMALCQYLEEHAEELNFQDAKILEIGAGPGLVSIVASILGAQVTATDLPD
VLGNLQYNLLKNTLQCTAHLPEVKELVWGEDLDKNFPKSAFYYDYVLASD
VVYHHYFLDKLLTTMVYLSQPGTVLLWANKFRFSTDYEFLDKFKQVFDTT
LLAEYPESSVKLFKGILKW
3D structure
PDB4mtl Human Methyltransferase-Like Protein 21C
ChainB
Resolution1.65 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SAH B V91 W92 A95 G120 D141 L142 W172 S193 D194 Y200 V47 W48 A51 G76 D97 L98 W128 S149 D150 Y156
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0008168 methyltransferase activity
GO:0016279 protein-lysine N-methyltransferase activity
GO:0031072 heat shock protein binding
Biological Process
GO:0006479 protein methylation
GO:0007519 skeletal muscle tissue development
GO:0008628 hormone-mediated apoptotic signaling pathway
GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
GO:0018022 peptidyl-lysine methylation
GO:0032259 methylation
GO:0071549 cellular response to dexamethasone stimulus
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0032991 protein-containing complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4mtl, PDBe:4mtl, PDBj:4mtl
PDBsum4mtl
PubMed
UniProtQ5VZV1|MT21C_HUMAN Protein-lysine methyltransferase METTL21C (Gene Name=METTL21C)

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