Structure of PDB 4mqj Chain B

Receptor sequence

>4mqjB (length=146) Species: 9606 (Homo sapiens)

VHFTEEDKATITSLWGKVNVEDAGGETLGRLLVVYPWTQRFFDSFGNLSS
ASAIMGNPKVKAHGKKVLTSLGDAIKHLDDLKGTFAQLSELHCDKLHVDP
ENFKLLGNVLVTVLAIHFGKEFTPEVQASWQKMVTGVASALSSRYH

3D structure

• PDB: 4mqj Structure of Wild-type Fetal Human Hemoglobin HbF
• Chain: B
• Resolution: 1.8 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	HEM	B	T38 F41 F42 H63 K66 S70 L88 H92 L96 V98 N102 F103 L106 L141	T38 F41 F42 H63 K66 S70 L88 H92 L96 V98 N102 F103 L106 L141

Gene Ontology

Molecular Function

• GO:0004601 peroxidase activity
• GO:0005344 oxygen carrier activity
• GO:0005515 protein binding
• GO:0019825 oxygen binding
• GO:0020037 heme binding
• GO:0031720 haptoglobin binding
• GO:0031721 hemoglobin alpha binding
• GO:0043177 organic acid binding
• GO:0046872 metal ion binding

Biological Process

• GO:0015670 carbon dioxide transport
• GO:0015671 oxygen transport
• GO:0042744 hydrogen peroxide catabolic process
• GO:0098869 cellular oxidant detoxification

Cellular Component

• GO:0005829 cytosol
• GO:0005833 hemoglobin complex
• GO:0031838 haptoglobin-hemoglobin complex
• GO:0072562 blood microparticle

External links

• PDB: RCSB:4mqj, PDBe:4mqj, PDBj:4mqj
• PDBsum: 4mqj
• UniProt: P69892|HBG2_HUMAN Hemoglobin subunit gamma-2 (Gene Name=HBG2)