Structure of PDB 4mg8 Chain B

Receptor sequence
>4mg8B (length=237) Species: 9606 (Homo sapiens) [Search protein sequence]
KNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADR
ELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKL
LFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSII
LLNSGVYTFKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILS
HIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHRL
3D structure
PDB4mg8 Structural and functional profiling of environmental ligands for estrogen receptors.
ChainB
Resolution1.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B I358 K362 L372 V376 E380 E542 I56 K60 L70 V74 E78 E230
BS02 27J B L346 L349 A350 E353 L387 M388 L391 M421 L44 L47 A48 E51 L85 M86 L89 M119
External links
PDB RCSB:4mg8, PDBe:4mg8, PDBj:4mg8
PDBsum4mg8
PubMed25260197
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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