Structure of PDB 4mb2 Chain B

Receptor sequence
>4mb2B (length=257) Species: 523850 (Thermococcus onnurineus NA1) [Search protein sequence]
VKIPKSHPRYWSLYYREKIIEGMEKGMTAKAGLIAHGRGEAFDYLIGERT
IEPAERAMRAAVAKLLLAENPVVSVNGNVAALVPKETIELARALNAKLEI
NLFYRTEDRVKAIAEELRKYDPEIELLGINPTKRIPGLEHERGKVDENGI
WKADVVVVPLEDGDRTEALVRMGKFVITIDLNPLSRSARMADITIVDNIV
RAYPRMTELAREMKDYSRGELIRIIEEYDNGKTLNDVLLHIRDRLTKLAE
GGIWRKK
3D structure
PDB4mb2 The crystal structure of a novel phosphopantothenate synthetase from the hyperthermophilic archaea, Thermococcus onnurineus NA1
ChainB
Resolution2.19 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.3.2.36: 4-phosphopantoate--beta-alanine ligase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP B A36 R39 L161 E162 D163 G164 D181 L182 R187 S188 N199 I200 A35 R38 L160 E161 D162 G163 D180 L181 R186 S187 N198 I199
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016874 ligase activity
GO:0016881 acid-amino acid ligase activity
Biological Process
GO:0015937 coenzyme A biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:4mb2, PDBe:4mb2, PDBj:4mb2
PDBsum4mb2
PubMed24021277
UniProtB6YXQ1|PPS_THEON 4-phosphopantoate--beta-alanine ligase (Gene Name=TON_1374)

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