Structure of PDB 4m0l Chain B

Receptor sequence
>4m0lB (length=396) Species: 273057 (Saccharolobus solfataricus P2) [Search protein sequence]
AWPKVQPEVNIGVVGHVDHGKTTLVQAITGIWTMTIKLGYAETNIGVCES
CKKPEAYVTEPSCKSCGSDDEPKFLRRISFIDAPGHEVLMATMLSGAALM
DGAILVVAANEPFPQPQTREHFVALGIIGVKNLIIVQNKVDVVSKEEALS
QYRQIKQFTKGTWAENVPIIPVSALHKINIDSLIEGIEEYIKTPYRDLSQ
KPVMLVIRSFDVNKKGGVIGGSIIQGLFKVDQEIKVLPGLRVEKQGKVSY
EPIFTKISSIRFGDEEFKEAKPGGLVAIGTYLDPSLTKADNLLGSIITLA
DAEVPVLWNIRIKYNLLERVVGAKEMLKVDPIRAKETLMLSVGSSTTLGI
VTSVKKDEIEVELRRPVAVWSNNIRTVISRQIAGRWRMIGWGLVEI
3D structure
PDB4m0l Conformational transitions in the gamma subunit of the archaeal translation initiation factor 2.
ChainB
Resolution2.6 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) D19 K22 T23 T46 H97
Catalytic site (residue number reindexed from 1) D18 K21 T22 T35 H86
Enzyme Commision number 3.6.5.3: protein-synthesizing GTPase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GDP B D19 G21 K22 T23 T24 N149 K150 D152 S184 A185 L186 D18 G20 K21 T22 T23 N138 K139 D141 S173 A174 L175
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0003743 translation initiation factor activity
GO:0003746 translation elongation factor activity
GO:0003924 GTPase activity
GO:0005515 protein binding
GO:0005525 GTP binding
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0001731 formation of translation preinitiation complex
GO:0006412 translation
GO:0006413 translational initiation
GO:0006414 translational elongation

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:4m0l, PDBe:4m0l, PDBj:4m0l
PDBsum4m0l
PubMed24598735
UniProtQ980A5|IF2G_SACS2 Translation initiation factor 2 subunit gamma (Gene Name=eif2g)

[Back to BioLiP]