Structure of PDB 4lus Chain B

Receptor sequence
>4lusB (length=374) Species: 272563 (Clostridioides difficile 630) [Search protein sequence]
KITVPTWAEINLDNLRFNLNNIKNLLEEDIKICGVIKADAYGHGAVEVAK
LLEKEKVDYLAVARTAEGIELRQNGITLPILNLGYTPDEAFEDSIKNKIT
MTVYSLETAQKINEIAKSLGEKACVHVKIDSGFQPNEESVQEIIELNKLE
YIDLEGMFTHFATADEEYTYKQANNYKFMSDKLDEAGVKIAIKHVSNSAA
IMDCPDLRLNMVRAGIILYGHYPSDDVFKDRLELRPAMKLKSKIGHIKQV
EPGVGISYGLKYTTTGKETIATVPIGYADGFTRIQKNPKVLIKGEVFDVV
GRICMDQIMVRIDKDIDIKVGDEVILFGEGEVTAERIAKDLGTINYEVLC
MISRRVDRVYMENNELVQINSYLL
3D structure
PDB4lus Structural and biochemical analyses of alanine racemase from the multidrug-resistant Clostridium difficile strain 630.
ChainB
Resolution2.1 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) K39 H167 R223 Y268 C314 D316
Catalytic site (residue number reindexed from 1) K37 H160 R213 Y258 C304 D306
Enzyme Commision number 5.1.1.1: alanine racemase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 TCE B T79 P81 K100 C126 T77 P79 K98 C124
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0008784 alanine racemase activity
GO:0016853 isomerase activity
GO:0030170 pyridoxal phosphate binding
Biological Process
GO:0006522 alanine metabolic process
GO:0009252 peptidoglycan biosynthetic process
GO:0030632 D-alanine biosynthetic process
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4lus, PDBe:4lus, PDBj:4lus
PDBsum4lus
PubMed25004969
UniProtQ180W0

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