Structure of PDB 4lnq Chain B

Receptor sequence
>4lnqB (length=192) Species: 10090 (Mus musculus) [Search protein sequence]
GAVLHEKPMTVMVLTATEPFNYKEGKENMFHATVATESKYYRVKVFNMDL
KEKFTENKFITISKYFNSSGILEINETATVSEAAPNQMFEVPKNIIRSAK
ETLKISKIKELDSGTLIYGVFAVEKKKVNDKSITFKIKDNEDNIKVVWDK
EQHNINYEKGDKLQLFSFHLRKGNGKPILHSGNHSFIKGEKL
3D structure
PDB4lnq Structural mechanism of DNA recognition by the p202 HINa domain: insights into the inhibition of Aim2-mediated inflammatory signalling.
ChainB
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B N182 D183 K184 S185 T187 K198 N129 D130 K131 S132 T134 K145 PDBbind-CN: Kd=1.33uM
BS02 dna B S166 H222 R224 K225 G226 S113 H169 R171 K172 G173 PDBbind-CN: Kd=1.33uM
Gene Ontology
Biological Process
GO:0002218 activation of innate immune response
GO:0035458 cellular response to interferon-beta

View graph for
Biological Process
External links
PDB RCSB:4lnq, PDBe:4lnq, PDBj:4lnq
PDBsum4lnq
PubMed24419611
UniProtQ9R002|IFI2_MOUSE Interferon-activable protein 202 (Gene Name=Ifi202)

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