Structure of PDB 4l4j Chain B

Receptor sequence
>4l4jB (length=182) Species: 9606 (Homo sapiens) [Search protein sequence]
SVFLFPPKPKDTLMISRTPEVTCVVVQFNWYVDGVEVHNAKTKPFRVVSV
LTVLHQDWLNGKEYKCKVSIEKTISKTKGQPREPQVYTLPPSREEMTKNQ
VSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPMLDSDGSFFLYSKLTV
DKSRWQQGNVFSCSVMHEALHNHYTQKSLSLS
3D structure
PDB4l4j An engineered Fc variant of an IgG eliminates all immune effector functions via structural perturbations.
ChainB
Resolution1.92 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 BMA B F241 F243 F3 F5
External links
PDB RCSB:4l4j, PDBe:4l4j, PDBj:4l4j
PDBsum4l4j
PubMed23872058
UniProtP01859|IGHG2_HUMAN Immunoglobulin heavy constant gamma 2 (Gene Name=IGHG2)

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