Structure of PDB 4kcx Chain B

Receptor sequence
>4kcxB (length=106) Species: 9606 (Homo sapiens) [Search protein sequence]
TNQLQYLQKVVLKDLWKHSFSWPFQRPVDAVKLQLPDYYTIIKNPMDLNT
IKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMAQALEKLFMQ
KLSQMP
3D structure
PDB4kcx Cyclin-dependent kinase inhibitor dinaciclib interacts with the acetyl-lysine recognition site of bromodomains.
ChainB
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 1QK B W50 P51 F52 V56 L61 D114 I115 W22 P23 F24 V28 L33 D86 I87 MOAD: Kd=37uM
External links
PDB RCSB:4kcx, PDBe:4kcx, PDBj:4kcx
PDBsum4kcx
PubMed24007471
UniProtQ58F21|BRDT_HUMAN Bromodomain testis-specific protein (Gene Name=BRDT)

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