Structure of PDB 4k7l Chain B

Receptor sequence
>4k7lB (length=102) Species: 9913 (Bos taurus) [Search protein sequence]
SNYCNQMMKSRNLTKDRCKPVNTFVHESLADVQAVCSQKNVACKNGQTNC
YQSYSTMSITDCRETGSSKYPNCAYKTTQANKHIIVACEGNPYVPVHFDA
SV
3D structure
PDB4k7l Crystal structure of RNase S with a [Hg(Cys2)] metal center in the S-peptide as a template for structure-based design of artificial metalloenzymes using peptide-protein complementation
ChainB
Resolution1.38 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) K41 H119 F120 D121
Catalytic site (residue number reindexed from 1) K19 H97 F98 D99
Enzyme Commision number 4.6.1.18: pancreatic ribonuclease.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B Y25 M29 R33 N34 N44 T45 F46 V47 H48 E49 S50 L51 V54 P117 H119 F120 Y3 M7 R11 N12 N22 T23 F24 V25 H26 E27 S28 L29 V32 P95 H97 F98
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding

View graph for
Molecular Function
External links
PDB RCSB:4k7l, PDBe:4k7l, PDBj:4k7l
PDBsum4k7l
PubMed
UniProtP61823|RNAS1_BOVIN Ribonuclease pancreatic (Gene Name=RNASE1)

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