Structure of PDB 4k6f Chain B

Receptor sequence
>4k6fB (length=245) Species: 216591 (Burkholderia cenocepacia J2315) [Search protein sequence]
KRIAVVTGGMGGLGEAVSIRLNDAGHRVVVTYSPNNTGADRWLTEMHAAG
REFHAYPVDVADHDSCQQCIEKIVRDVGPVDILVNNAGITRDMTLRKLDK
VNWDAVIRTNLDSVFNMTKPVCDGMVERGWGRIVNISSVNGSKGSVGQTN
YAAAKAGMHGFTKSLALEIARKGVTVNTVSPGYLATKMVTAIPQDILDTK
ILPQIPAGRLGKPEEVAALVAYLCSEEAGFVTGSNIAINGGQHMH
3D structure
PDB4k6f X-ray crystal structure of a putative Acetoacetyl-CoA reductase from Burkholderia cenocepacia bound to the co-factor NADP
ChainB
Resolution1.5 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) G14 N104 S140 Y153 K157
Catalytic site (residue number reindexed from 1) G12 N102 S138 Y151 K155
Enzyme Commision number 1.1.1.36: acetoacetyl-CoA reductase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAP B G10 Y34 S35 N38 V60 D61 V62 A89 G90 I91 G8 Y32 S33 N36 V58 D59 V60 A87 G88 I89
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0016491 oxidoreductase activity
GO:0018454 acetoacetyl-CoA reductase activity
Biological Process
GO:0042619 poly-hydroxybutyrate biosynthetic process
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4k6f, PDBe:4k6f, PDBj:4k6f
PDBsum4k6f
PubMed
UniProtB4EAU4

[Back to BioLiP]