Structure of PDB 4k19 Chain B

Receptor sequence
>4k19B (length=163) Species: 9606 (Homo sapiens) [Search protein sequence]
SDLIPAPPLSKVPLQQNFQDNQFQGKWYVVGLANAILREDKPQKMYATIY
ELDKSYNVTSVLFRKKKCDYWIRTFVPGSQPGEFTLGNIKSYPGLTSYLV
RVVSTNQHAMVFFKKVSQNREYFKITLYGRTKELTKENFIRFSKSLGLPE
NHIVFPVPIDQCI
3D structure
PDB4k19 Siderocalin Outwits the Coordination Chemistry of Vibriobactin, a Siderophore of Vibrio cholerae.
ChainB
Resolution2.74 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 1OD B W79 Y100 L103 Y106 F123 K125 F133 K134 W71 Y92 L95 Y98 F113 K115 F123 K124 BindingDB: Kd=34nM
Gene Ontology
Molecular Function
GO:0005506 iron ion binding
GO:0005515 protein binding
GO:0036094 small molecule binding
GO:0042802 identical protein binding
GO:0140315 iron ion sequestering activity
GO:1903981 enterobactin binding
Biological Process
GO:0006826 iron ion transport
GO:0006915 apoptotic process
GO:0015891 siderophore transport
GO:0042742 defense response to bacterium
GO:0045087 innate immune response
GO:0120162 positive regulation of cold-induced thermogenesis
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0031410 cytoplasmic vesicle
GO:0035580 specific granule lumen
GO:0060205 cytoplasmic vesicle lumen
GO:0070062 extracellular exosome

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:4k19, PDBe:4k19, PDBj:4k19
PDBsum4k19
PubMed23755875
UniProtP80188|NGAL_HUMAN Neutrophil gelatinase-associated lipocalin (Gene Name=LCN2)

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