Structure of PDB 4k17 Chain B

Receptor sequence
>4k17B (length=660) Species: 10090 (Mus musculus) [Search protein sequence]
ESSDVPRELMESIKDVIGRKIKISVKKKVKLEVKGDRVENKVLVLTSCRA
FLLSARIPSKLELTFSYLEIHGVICHKPAQMVVETEKCNMSMKMVSPEDV
SEVLAHIGTCLRRIFPGLSPLRIMKKVSMEPSERLASLQALWDSQTLAEP
GPCGGFSQMYACVCDWLGFSYKEEVQWDVDTIYLTQDTRELNLQDFSHLE
HRDLIPIIAALEYNQWFTKLSSKDLKLSTDVCEQILRVVSRSNRLEELVL
ENAGLRIDFAQKLAGALAHNPNSGLHTINLAGNSLEDRGVSSLSIQFAKL
PKGLKHLNLSKTSLSPKGVNSLCQSLSANPLTASTLTHLDLSGNALRGDD
LSHMYNFLAQPNTIVHLDLSNTECSLEMVCSALLRGCLQCLAVLNLSRSV
FSHRKGKEVPPSFKQFFSSSLALIQINLSGTKLSPEPLKALLLGLACNHS
LKGVSLDLSNCELGHCLRSGGAQVLEIHNITSLDISDNGLESDLSTLIVW
LSKNRSIQHLALGKNFNNMKSKNLTPVLDNLVQMIQDEDSPLQSLSLADS
KLKAEVTIIINALGSNTSLTKVDISGNGMGDMGAKMLAKALQINTKLRTV
IWDKNNITAQGFQDIAVAMEKNYTLRFMPIPMYDAAQALKTNPEKTEEAL
QKIENYLLRN
3D structure
PDB4k17 CARMIL leading edge localization depends on a non-canonical PH domain and dimerization.
ChainB
Resolution2.895 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 OHB B E380 M381 S384 E377 M378 S381
External links
PDB RCSB:4k17, PDBe:4k17, PDBj:4k17
PDBsum4k17
PubMed24071777
UniProtQ6EDY6|CARL1_MOUSE F-actin-uncapping protein LRRC16A (Gene Name=Carmil1)

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