Structure of PDB 4jol Chain B
Receptor sequence
>4jolB (length=60) Species:
9606
(Homo sapiens) [
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IDHRLTDREWAEEWKHLDHLLNCIMDMVEKTRRSLTVLRRCQEADREELN
YWIRRYSDAE
3D structure
PDB
4jol
A stable transcription factor complex nucleated by oligomeric AML1-ETO controls leukaemogenesis.
Chain
B
Resolution
2.906 Å
3D
structure
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Enzymatic activity
Enzyme Commision number
?
Interaction with ligand
Site
#
Ligand
Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01
peptide
B
E501 H504 H507 L508
E13 H16 H19 L20
BS02
peptide
B
S522 V525
S34 V37
Gene Ontology
Molecular Function
GO:0003714
transcription corepressor activity
Biological Process
GO:0045892
negative regulation of DNA-templated transcription
View graph for
Molecular Function
View graph for
Biological Process
External links
PDB
RCSB:4jol
,
PDBe:4jol
,
PDBj:4jol
PDBsum
4jol
PubMed
23812588
UniProt
Q06455
|MTG8_HUMAN Protein CBFA2T1 (Gene Name=RUNX1T1)
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