Structure of PDB 4jol Chain B

Receptor sequence
>4jolB (length=60) Species: 9606 (Homo sapiens) [Search protein sequence]
IDHRLTDREWAEEWKHLDHLLNCIMDMVEKTRRSLTVLRRCQEADREELN
YWIRRYSDAE
3D structure
PDB4jol A stable transcription factor complex nucleated by oligomeric AML1-ETO controls leukaemogenesis.
ChainB
Resolution2.906 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide B E501 H504 H507 L508 E13 H16 H19 L20
BS02 peptide B S522 V525 S34 V37
Gene Ontology
Molecular Function
GO:0003714 transcription corepressor activity
Biological Process
GO:0045892 negative regulation of DNA-templated transcription

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Molecular Function

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Biological Process
External links
PDB RCSB:4jol, PDBe:4jol, PDBj:4jol
PDBsum4jol
PubMed23812588
UniProtQ06455|MTG8_HUMAN Protein CBFA2T1 (Gene Name=RUNX1T1)

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